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Obesity and Metabolic Syndrome

Obesity and metabolic syndrome are characterized by increased fat accumulation, especially in the abdomen. This is coupled with metabolic disturbances such as insulin resistance, hypertension, and dyslipidemia. Dysbiosis in the gut microbiome can affect energy balance and the storage of fat by affecting metabolism and promoting inflammation, throughout the body. This can lead to an increased absorption of dietary fats, alterations in bile acid metabolism, and changes in gut permeability. The increased inflammatory response can lead to disruptions in insulin signaling and glucose metabolism. Addressing gut dysbiosis through dietary modifications, health wellness, lifestyle modifications and mental health, may benefit in managing these metabolic conditions.